Genome sequence of Streptomyces antioxidans MUSC 164T isolated from mangrove forest

Abstract

Members of Streptomyces genus are well known to produce bioactive compounds of various 26 structures[1-3]. Having a complicated development life cycle with the ability to form spores, 27 Streptomyces species are ubiquitous in nature and can be found in interesting places like deep 28 sea, hot springs and also mangrove forest[3-11]. Streptomyces antioxidans MUSC 164T was 29 originally isolated from mangrove forest in the east coast of Peninsular Malaysia and has been 30 deposited at two culture collection centers (=DSM 101523T = MCCC 1K01590T)[12,13]. After 31 rounds of in vitro screening using human neuronal cell line (i.e. SH-SY5Y), the extract of 32 MUSC 164T was found to possess significant neuroprotective effect against hydrogen 33 peroxide[13]. Here we report the high quality genome sequence of MUSC 164T, while 34 discussing its genome potential to produce pharmaceutically important compounds.