Clinical Perspective: Potential use of Polio Vaccine for COVID-19 Prevention
Abstract
The novel coronavirus disease 2019 (COVID-19) pandemic that caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a detrimental effect on every fabric of society. Childhood poliovirus vaccination is believed to have a causative link between SARS-CoV-2 immunity. This report was aimed to explore the effect and evidence of the polio vaccine in preventing COVID-19 infection. Literature has shown that the oral polio vaccine produces broader protection against unrelated pathogens. Both the poliovirus and coronavirus belong to the same positive-strand RNA virus category, which can be eliminated by common innate immunity mechanisms. Vaccination against the poliovirus triggers an adaptive humoral immune response that raises antibodies that cross-react with SARS-CoV-2.
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