A Rapid Method for the Retrieval of Bioactive Xanthone from Garcinia Mangostana: A Case Study of α-Mangostin
AbstractNatural products have been used as the functional food and alternative treatment to combat various diseases for centuries. A handful of bioactive compounds that are available clinically such as antibiotic, anti-neurodegeneration, and anticancer drugs were derived from natural products. Recent study showed that α-mangostin, a natural occurring prenylated xanthone, possesses a wide variety of pharmacological activities including anti-cancer, anti-inflammation, anti-bacterial, anti-viral, and anti-neurodegenerative. In view of the pharmacological importance of α-mangostin, a rapid extraction method is paramount importance to recover the α-mangostin from natural resources to cope the therapeutic needs and potential for future clinical translation. The yield of α-mangostin was 9.2 g/kg DW. This study presents a simple, cost effective, and rapid extraction with identification of α-mangostin from the pericarp of the mangosteen fruit.
Author(s) shall retain the copyright of their work and grant the Journal/Publisher right for the first publication with the work simultaneously licensed under:
Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). This license allows for the copying, distribution and transmission of the work, provided the correct attribution of the original creator is stated. Adaptation and remixing are also permitted.
This broad license intends to facilitate free access to, as well as the unrestricted reuse of, original works of all types for non-commercial purposes.
The author(s) permits HH Publisher to publish this article that has not been submitted elsewhere.